Squigglesembly
From apm
Squigglesembly is the usage of only a few shape complementary interfaces to
achieve near arbitrarily controllable filling of 2D or 3D space.
Contents
Prerequisites for squigglesembly
- interfaces encode only a few simple turns (like left & right & maybe straight for 2D)
- assembly proceeds as iterative self-assembly
Benefits of squigglesembly
Squigglesembly may help in overcoming limitaions in
termination control that de-novo proteins face
due tue is teducing the number of mutually orthogonal
shape complementary interfaced needed.
(Choice of name: "squiggly" for the squiggly path that needs to be built up to fully fill a 2D or 3D space with a 1D line in a systematic way)
Delineation form other concepts
Squigglesembly is not to confuse with the squiggly lines of foldamer backbones. – Proteins do self folding – structural DNA nanotechnology one-pot self-assembly
