# Method of assembly

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## Self-assembly

Radical Abundance:
"Let parts move at random and require each part to
encounter and bind to its own special place"


Since nano-biology uses self assembly extensively today (in the molecular sciences) self assembly is perceived as natural in the nanoscale although its very alien at the makroscale.

• putting things together requires no machinery

• all pieces in a complex non-periodic structure need to have unique shapes like in a puzzle which makes the pieces bigger
• all bonds need to be weak such that wrong matches open up again
• finished pieces necessarily have irregular seams

These issues make design difficult. (folded polymeric chains)

## Stereotactic control

(See: mechanosynthesis)
It's the common sense method of putting things by pick and place together e.g. sticking sleeves on axles.

Radical Abundance:
"the ability to guide molecular assembly by guiding molecular motions ... move parts into place and put them together"


Since nano-biology uses stereotactic control only in loose and somewhat hidden ways (in the molecular sciences) self assembly is perceived as rather alien in the nano-scale although it can work perfectly well.

Sidenote: Why not call it "robotic control"? [todo: link article "why I hate nanobots"] Like the term "nanotechnology" the term "robot" is not well defined and can be bent a lot. The term "stereotactic" comes like a quick google serch shows from brain surgery where you need everything in a global coordinate system and need to tightly constrain any shaking to the minimum - a quite fitting therm here.

• putting things together requires advanced machinery

• all pieces in a complex non-periodic structure can have identical shape and minimal size.
• all bonds can be as strong as possible
• finished pieces can have maximally smooth seams

## Loose stereotactic control with self assisted assembly

It seems that to remove the sole disadvantage of stereotactic control one needs the advantages of stereotactic control. (see: why advanced APM systems are not a castle in the sky).

By combining loose stereotactic control with self-assembly one can climb an incremental path to full stereotactic control.

### Characteristics of intermediate systems

• usage of bigger building blocks and sufficiently distinct binding sites in position and possibly shape
• usage of "soft machines" for the selection of the local binding site environment
• usage of snap in / localized self-assembly / self-centering / self-alignment / self assisted assembly

## Related

• 1D brownian walk; ribosome; analogy to transport along microtubuli
• Mechanosynthesis