Catalysis construction kit approach
From apm
This approach involves getting to a positional assembly kinematic loop ASAP.
It is basically the functional block construction kit approach but
with selfassembled actuation elements of some sorts in order to better facilitate chemical reactions.
Or at least sensing like in a molecular universal testing machine.
Since foldamer based artificial catalysis is a very hard problem
a sensing/detecting is possibly a sub-problem to split off and solve first.