Difference between revisions of "Ribosome like chain assembly"

Revision as of 16:59, 14 April 2021

This is is about assembly metods that

• take in in raw more or less pre(self)assembled parts
• push out a chain that folds itself up into a bigger product

Actual ribosomes

• Taken in are amino acids linked to much bigger TRNA handles
• Pushed out are protein chains that fold up right away (thermally driven)

Often (always?) membrane proteins assemble right away directly into a target lipid membrane.
Btw: How do the chaperone folding helper proteins come close enough when there is quite a bit of obstruction by the ribosome?

Foldamer printers making parts bigger than their build volume

This could work more like folding up chain of via hinged linked cuboid (or other highly geometric) blocks.
(wiki-TODO: add illustrative image for that idea)