Iterative self-assembly
From apm
(Redirected from Iterative self assembly)
Iterative self assembly is letting things fully self-assemble before mixing in the next kind(s) of building blocks.
- All reactive sites that shall not be filled with one of the parts in the next wash-in should
be fully saturated before proceeding with the next step. - There needs to be a way for sufficiently thorough wash-outs and wash-ins such that
the desired products keep staying in the reaction volume. E.g. attachment to large surfaces provided by some sort of larger scale micro-beads.
Iterative assembly can provide a basis for
circumventing the limitations of de-novo proteins in termination control.
Sub-classification
- added parts are roughly of same size – no external pre-selfassembly steps happening
- hierarchical selfassembly – combining products of preceding in parallel executed one-pot self-assembly processes
– this modifies above's constraints a bit (wiki-TODO: discuss that)
Related
The complement to iterative self-assembly is one-pot self-assembly.
Iterative self-assembly can also be a sequence of one-pot self-assembly steps.
