Difference between revisions of "Highly polycyclic small molecule"
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Polycycles not just in in 2D but also (and perhaps predominately so) in 3D. <br> | Polycycles not just in in 2D but also (and perhaps predominately so) in 3D. <br> | ||
Preferably with no free rotational degrees of freedom in the molecule. | Preferably with no free rotational degrees of freedom in the molecule. | ||
| + | |||
| + | Such molecules may eventual provide a way out of the <br> | ||
| + | [[fat finger problem]] vs [[floppy finger problem]] dilemma <br> | ||
| + | that one faces with natural proteins. | ||
| + | |||
| + | '''Highly polycyclic small molecule could be integrated as an artificial side-chain in synthetic peptides.'''<br> | ||
| + | For integration of different technologies see page: <br> | ||
| + | [[Combining advantages of different selfassembly technologies]] | ||
== Examples == | == Examples == | ||
Revision as of 15:15, 18 May 2022
This page is about small molecules that feature a lot of polycyclic elements.
Polycycles not just in in 2D but also (and perhaps predominately so) in 3D.
Preferably with no free rotational degrees of freedom in the molecule.
Such molecules may eventual provide a way out of the
fat finger problem vs floppy finger problem dilemma
that one faces with natural proteins.
Highly polycyclic small molecule could be integrated as an artificial side-chain in synthetic peptides.
For integration of different technologies see page:
Combining advantages of different selfassembly technologies
Examples
- 2D polycyclic
- no rotational degrees of freedom
Molecules close to adamantane in structure. These are close in nature to diamond. One proposal are adamantanes with corners substituted with boron sand or nitrogen.
- Either alternatingly wit four nitrigens and 4 borons
- Or all the same either all 8 substituted with nitrogen (adamanzane) or all 8 substituted with boron.
Misc
Aromatic polycyclic compounds are also often optically active and potentially of interest as basis for optically activated nanoscale actuators.
Related
- Stiffness
- Combining advantages of different selfassembly technologies
- Spiroligoners
- Organometallic compound
- Molecule fragments
External links
Wikipedia
- Adamanzane – adamantane with corners substituted by nitrogen atoms
- The boron analogon to adamanzane
- The alternating nitrogen boron version of adamanzane
- Category: Polycyclic organic compounds
- Category: Polycyclic onaromatic hydrocarbons
- Category: Boron heterocycles
- Heterocyclic compound
- Category: Heterocyclic compounds
- Category: Nitrogen heterocycles
Exotic miscellaneous:
