View source for Folded-foldamer pushing approach

{{stub}}

This page is about the possible approach of <br>
pushing (or pulling if possible) small already self-assembled structures around on a surface  <br>
in order to assemble them via [[SPM]] ([[Top down positional assembly]]) to bigger structures. <br>
* Small means: All the input parts have undergone just the first level of [[hierarchical self-assembly]]. <br>
* Structures might e.g. include stiff & sturdy designed [[de-novo proteins]].

'''This approach competes against [[self-assembly]].''' <br>
And this is a symptom of the [[Positional assembly redundancy blockade]].

== PROs & CONs ==

'''Advantages:''' <br>
Basically evading development difficulties of selfassembly. E.g.no need to develop: <br>
– large orthogonal sets of complementary surfaces or <br>
– [[iterative selfassembly]] <br>
– [[squigglesembly]], [[circumsembly]], ...

'''Difficulties for pushing folded proteins around by SPM may include:''' <br>
– tip bluntness at the larger scale of softer proteins <br>
– SPM control for larger vertical motions being very limited <br>
– only perhaps: crushing the specimen issues

'''Inferiorities relative to self-assembly when working include:''' <br>
– only one product (or a few with additional difficulties) rather than several orders of magnitude simultaneously <br>
– assembly of each new product takes long

== Related ==

* [[Positional assembly redundancy blockade]]
* [[Incremental path]]
* [[Top down positional assembly]]
* [[self-assembly]], [[positional assembly]]
* [[Direct path]]