Hierarchical selfassembly
Up: General concept: Convergent assembly
Hierarchical selfassembly (also convergent selfassembly) is the case when
structures get self-assembled from parts that themselves where previously self-assembled.
This implies that hierarchical selfassembly is a subform of iterative self-assembly.
(Iterative self-assembly also covers repeated additions of parts of the same size.)
Note that hierarchical selfassembly is not exclusive to thermally driven self-assembly.
Hierarchical selfassembly is also applicable to:
Experimental demonstrations
As of time of last review (2024-03) hierarchical selfassembly has been …
- … impressively demonstrated with 3D structural DNA nanotechnology.
- … demonstrated with de-novo proteins
with the large caveat that of missing termination control.
Note that terminating structures like rings or balls is not a form of termination control as defined in this wiki.
Rotation symmetry is an infinite symmetry (just like translation symmetry in a crystal) just that it covers over itself.
Hierarchical selfassembly of 3D structural DNA nanotechnology (3D-SDN)
Second level of self-assembly is self finding of the hexagonal building blocks. Shown.
Here this goes one step further in attempting to make a sandard set of blocks for the second assembly level such that arbitrary larger structures can be built quickly and easily. Custom blocks may be more versatile but are one off solutions for specific desireed geometeries. Images from paper: "Finite Assembly of Three‐Dimensional DNA Hierarchical Nanoarchitectures through Orthogonal and Directional Bonding" (click image for sources) – Related to this are: topological atomic precision & termination control.
Related
- Selfassembly level in self assembly
- complementary is: hierarchical positional assembly here
covered by page convergent assembly & assembly level in positional assembly