Diffusion slowdown blockade: Difference between revisions
added section == Delineation to slowdown from finding sparse binding partners == |
→Delineation to slowdown from finding sparse binding partners: linebreaks and link to [thermally driven self assembly]] |
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== Delineation to slowdown from finding sparse binding partners == | == Delineation to slowdown from finding sparse binding partners == | ||
This can lead to severe slowdown. | This can lead to severe slowdown. <br> | ||
But this can be easier fixed by switching to other strategies | But this can be easier fixed by switching to other strategies <br> | ||
like going from more [[self finding]] to more [[self folding]] | like going from more [[self finding]] to more [[self folding]] type of [[thermally driven self assembly]]. <br> | ||
* more concretely: templating strands in [[structural DNA nanotechnology]] | * more concretely: templating strands in [[structural DNA nanotechnology]] | ||
* more abstractly: increasing [[effective concentration]] | * more abstractly: increasing [[effective concentration]] | ||
The issue is that even with that optimized to the maximum | The issue is that even with that optimized to the maximum <br> | ||
the diffusion speed blockade still remains. | the diffusion speed blockade still remains. | ||
Revision as of 14:56, 9 July 2026
When going to larger sizes one faces:
- much lower speeds – typically much below the speed of sound
- much larger distances
- => much much lower random part encounter rates
The encounter rate of small molecule sized parts at the nanoscale due to thermal motion is mindbogglingly high.
To get an intuitive feel about just how much macroscale is at a disadvantage see page: The speed of atoms
This obstacle can be hit when scaling termination control and site addressability in
technologies that use thermally driven self-assembly to rather large scales.
Like e.g. already the casein the higher selfassembly levels of structural DNA nanotechnology.
Delineation to slowdown from finding sparse binding partners
This can lead to severe slowdown.
But this can be easier fixed by switching to other strategies
like going from more self finding to more self folding type of thermally driven self assembly.
- more concretely: templating strands in structural DNA nanotechnology
- more abstractly: increasing effective concentration
The issue is that even with that optimized to the maximum
the diffusion speed blockade still remains.
Related
External links
(wiki-TODO: Add links to videos of macroscale demos of selfassembly of 3D printed virus-shell models with magnets inside.)