Foldamer R&D - Revision history

Apm at 16:10, 29 March 2026

2026-03-29T16:10:15Z

← Older revision		Revision as of 18:10, 29 March 2026
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	* The suspected lignin pileup in the [https://en.wikipedia.org/wiki/Carboniferous Carboniferous] epoch of earths history.		* The suspected lignin pileup in the [https://en.wikipedia.org/wiki/Carboniferous Carboniferous] epoch of earths history.
	* The talk doesn't look beyond towards gemstone based systems as far term goal. Partially [[brownian technology path]]?		* The talk doesn't look beyond towards gemstone based systems as far term goal. Partially [[brownian technology path]]?

			[[category:Incremental path]]

Apm: /* Related */

2021-03-13T11:33:46Z

← Older revision		Revision as of 13:33, 13 March 2021
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	= Related =		= Related =

			* This is part of [[Present-forward development]] as opposed to [[Future-backward development]]
	* [[Incremental path]]		* [[Incremental path]]
	* [[Reached milestones in foldamer R&D]]		* [[Reached milestones in foldamer R&D]]

Apm: Fixed headline hierarchy

2021-03-13T11:32:21Z

Fixed headline hierarchy

← Older revision		Revision as of 13:32, 13 March 2021
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	* Open: https://cryoem.ucla.edu/uploads/image/pdfs/2015_gonen.pdf		* Open: https://cryoem.ucla.edu/uploads/image/pdfs/2015_gonen.pdf

	== Related ==		= Related =

	* [[Incremental path]]		* [[Incremental path]]
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	* Microfluidics		* Microfluidics

	== External links ==		= External links =

	* Wikipedia: [https://en.wikipedia.org/wiki/Foldamer Foldamer]		* Wikipedia: [https://en.wikipedia.org/wiki/Foldamer Foldamer]

Apm: Moved list of papers over from page: Present-forward development

2021-03-13T11:31:52Z

Moved list of papers over from page: Present-forward development

@@ Line 5: / Line 5: @@
 * peptidomimetics like peptoids (& beta-peptides)
 * spiroligomers
 == Related ==

Apm: /* External links */ relativated by adding "suspected"

2017-08-15T16:04:15Z

External links: relativated by adding "suspected"

← Older revision		Revision as of 18:04, 15 August 2017
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	* Bootstrapping of the synthesis of the fundamental spiroligomer building blocks		* Bootstrapping of the synthesis of the fundamental spiroligomer building blocks
	* The "indestructibility" of spiroligomers raise the issue of the waste problem with POPs (persistent organic pollutants) -- See: [[Recycling]]		* The "indestructibility" of spiroligomers raise the issue of the waste problem with POPs (persistent organic pollutants) -- See: [[Recycling]]
	* The lignin pileup in the [https://en.wikipedia.org/wiki/Carboniferous Carboniferous] epoch of earths history.		* The suspected lignin pileup in the [https://en.wikipedia.org/wiki/Carboniferous Carboniferous] epoch of earths history.
	* The talk doesn't look beyond towards gemstone based systems as far term goal. Partially [[brownian technology path]]?		* The talk doesn't look beyond towards gemstone based systems as far term goal. Partially [[brownian technology path]]?

Apm: /* External links */ elaborated by adding: "indestructibility" of spiroligomers

2017-08-15T16:03:04Z

External links: elaborated by adding: "indestructibility" of spiroligomers

← Older revision		Revision as of 18:03, 15 August 2017
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	* Invention (and market introduction) of covalent protein crosslinking technology		* Invention (and market introduction) of covalent protein crosslinking technology
	* Bootstrapping of the synthesis of the fundamental spiroligomer building blocks		* Bootstrapping of the synthesis of the fundamental spiroligomer building blocks
	* The waste problem with POPs (persistent organic pollutants) -- See: [[Recycling]]		* The "indestructibility" of spiroligomers raise the issue of the waste problem with POPs (persistent organic pollutants) -- See: [[Recycling]]
	* The lignin pileup in the [https://en.wikipedia.org/wiki/Carboniferous Carboniferous] epoch of earths history.		* The lignin pileup in the [https://en.wikipedia.org/wiki/Carboniferous Carboniferous] epoch of earths history.
	* The talk doesn't look beyond towards gemstone based systems as far term goal. Partially [[brownian technology path]]?		* The talk doesn't look beyond towards gemstone based systems as far term goal. Partially [[brownian technology path]]?

Apm: /* External links */ added three more relevant points

2017-08-15T16:01:39Z

External links: added three more relevant points

← Older revision		Revision as of 18:01, 15 August 2017
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	* Iterative design of early forms of [[Kaehler bracket]]s <br>optimization of a stiff backbone to get functional groups as close as possible to a fixed predefined configuration (that may have been stolen from a natural protein)		* Iterative design of early forms of [[Kaehler bracket]]s <br>optimization of a stiff backbone to get functional groups as close as possible to a fixed predefined configuration (that may have been stolen from a natural protein)
	* [[General software issues]] – programming language limitations, the dreaded interface problem, <br>"deforresting" unnecessary computer algebra reevaluations (a problem also showing up in volumetric 3D modelling aka distance field based [[3D modelling]]; [[Design levels]]),<br> the need for derivation towers (scalar,vector,tensor) (automatic derivation - links to Conal Elliotts work)		* [[General software issues]] – programming language limitations, the dreaded interface problem, <br>"deforresting" unnecessary computer algebra reevaluations (a problem also showing up in volumetric 3D modelling aka distance field based [[3D modelling]]; [[Design levels]]),<br> the need for derivation towers (scalar,vector,tensor) (automatic derivation - links to Conal Elliotts work)
			* Going deep down the rabbit-hole to reach a far term target (in an highly non-obvious way for outsiders).<br> Sidenote: That's exactly where natural [[evolution]] has severe limitations.
			* Invention (and market introduction) of covalent protein crosslinking technology
			* Bootstrapping of the synthesis of the fundamental spiroligomer building blocks
	* The waste problem with POPs (persistent organic pollutants) -- See: [[Recycling]]		* The waste problem with POPs (persistent organic pollutants) -- See: [[Recycling]]
	* The lignin pileup in the [https://en.wikipedia.org/wiki/Carboniferous Carboniferous] epoch of earths history.		* The lignin pileup in the [https://en.wikipedia.org/wiki/Carboniferous Carboniferous] epoch of earths history.
	* The talk doesn't look beyond towards gemstone based systems as far term goal. Partially [[brownian technology path]]?		* The talk doesn't look beyond towards gemstone based systems as far term goal. Partially [[brownian technology path]]?

Apm: /* External links */ no mention of gemstone as far term goal

2017-08-14T17:52:14Z

External links: no mention of gemstone as far term goal

← Older revision		Revision as of 19:52, 14 August 2017
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	* The waste problem with POPs (persistent organic pollutants) -- See: [[Recycling]]		* The waste problem with POPs (persistent organic pollutants) -- See: [[Recycling]]
	* The lignin pileup in the [https://en.wikipedia.org/wiki/Carboniferous Carboniferous] epoch of earths history.		* The lignin pileup in the [https://en.wikipedia.org/wiki/Carboniferous Carboniferous] epoch of earths history.
			* The talk doesn't look beyond towards gemstone based systems as far term goal. Partially [[brownian technology path]]?

Apm: /* External links */ added link to a presentation of Christian Schafmeister + some discussion of that

2017-08-14T17:47:26Z

External links: added link to a presentation of Christian Schafmeister + some discussion of that

← Older revision		Revision as of 19:47, 14 August 2017
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	* Wikipedia: [https://en.wikipedia.org/wiki/De_novo_protein_structure_prediction De_novo_protein_structure_prediction]		* Wikipedia: [https://en.wikipedia.org/wiki/De_novo_protein_structure_prediction De_novo_protein_structure_prediction]
	* Wikipedia: [https://en.wikipedia.org/wiki/Peptidomimetic Peptidomimetic][https://en.wikipedia.org/wiki/Peptoid Peptoid][https://en.wikipedia.org/wiki/Beta-peptide Beta-peptide]		* Wikipedia: [https://en.wikipedia.org/wiki/Peptidomimetic Peptidomimetic][https://en.wikipedia.org/wiki/Peptoid Peptoid][https://en.wikipedia.org/wiki/Beta-peptide Beta-peptide]

			'''Video:'''
			"Clasp: Common Lisp using LLVM and C++ for Molecular Metaprogramming" [https://www.youtube.com/watch?v=8X69_42Mj-g]<br>
			Published on Jun 15, 2015 – Google Tech Talk – June 9, 2015 – Presented by Christian Schafmeister.

			This video also brings up topics like:
			* The importance of [[stiffness]] – double linked backbones prevent rotations making resulting structures much easier to desing and more predictable
			* Iterative design of early forms of [[Kaehler bracket]]s <br>optimization of a stiff backbone to get functional groups as close as possible to a fixed predefined configuration (that may have been stolen from a natural protein)
			* [[General software issues]] – programming language limitations, the dreaded interface problem, <br>"deforresting" unnecessary computer algebra reevaluations (a problem also showing up in volumetric 3D modelling aka distance field based [[3D modelling]]; [[Design levels]]),<br> the need for derivation towers (scalar,vector,tensor) (automatic derivation - links to Conal Elliotts work)
			* The waste problem with POPs (persistent organic pollutants) -- See: [[Recycling]]
			* The lignin pileup in the [https://en.wikipedia.org/wiki/Carboniferous Carboniferous] epoch of earths history.

Apm: /* Related */ added link to yet unwritten page Creating Reached milestones in foldamer R&D

2017-08-05T08:17:46Z

Related: added link to yet unwritten page Creating Reached milestones in foldamer R&D

← Older revision		Revision as of 10:17, 5 August 2017
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	* [[Incremental path]]		* [[Incremental path]]
			* [[Reached milestones in foldamer R&D]]
	* [[Self folding]]		* [[Self folding]]
	* covalent cross interlinking (increasing [[stiffness]])		* covalent cross interlinking (increasing [[stiffness]])