View source for Reached milestones in foldamer R&D

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{{wikitodo|add technology dependency diagram}}
{{wikitodo|reference all the associated papers}}

One can identify: 
* progress in control of self assembly 
* progress in means of actuation of the self assembled structures

== Classified by foldamer type ==

=== DNA as building material ===

Highly relevant:

* ending reliance on viral DNA => fully abiotic process
* proof of atomic precision in DNA brick structures (via cryo-TEM-tomography)
* abstraction over low base part symmetry (orthorhombic and hexagonal - slight twist deformation though)
* introduction of highly localized compliance (aka hinges) and sliding rails
* [[convergent self-assembly|two stage hierarchical self assembly]] (reversible second stage via stiff shape complementarity & salt concentration)
* demonstration of subatomic positional precision (via a hinge mechanism)
* multi micron scale atomically precise pegboard structures
* demonstration of fast electrostatic actuation of structural DNA assemblies
* ....

Maybe less relevant:

* DNA walkers (unidirectional & bidirectional) -- {{wikitodo|link related online learning game}}
* spacial digital counting (still crude) -- {{wikitodo|link related talk video}}
* stiff DNA triangle cages (note: deltahedrons are stiff polyhedrons)
* DNA tensegrity

=== de-novo proteins ===

* high symmetry de-novo protein sheets
* ...

=== Spiroligomers ===

* ... {{todo|investigate conducted research}}

== Makroscale base technologies ==

* DNA oglionucleotide synthesis
* Microfluidics (?)

== Related ==

* [[Foldamer R&D]]
* pending / outstanding milestone [[Mechanical demultiplexing]]
* [[Incremental path]]